Ribodorm Project

About the Ribodorm project

In a new project funded by the BBSRC and Leverhulme Trust, we study how ribosomes are switched off when cells become dormant, and how they reactivate when cells "awaken" from dormancy. 

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To understand cell dormancy and ribosome hibernation across scales, we employ a multimodal approach: We combine omics, confocal microscopy, X-ray tomography, cryo-electron tomography, and cryo-electron microscopy to study these processes from cells to atoms.  

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To elucidate how ribosome hibernation evolved in eukaryotes, we follow a cross-species approach, comparing mammals, fungi, and plants.